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KMID : 0948320040040020138
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Konyang Medical Journal
2004 Volume.4 No. 2 p.138 ~ p.142
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Effect of Normal Saline, Lidocaine and Sodium Bicarbonate on Pain and Withdrawal Movement during Injection of Rocuronium
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Jung Sung-Mee
Kwon Hee-Uk
Kang Po-Soon
Lim Young-Su
Ko Na-Young
Park Cheol-Woo
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Abstract
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Background: We investigated the efficacy of premixed normal saline, lidocaine and sodium bicarbonate in reducing pain and withdrawal movement caused by intravenous injection of rocuronium.
Methods: Seventy four adult patients were randomly allocated into three groups in a double-blinded, prospective study. Rocuronium 50 mg/5 ml was mixed with Same volume of normal saline (Group S, n=29), 2% lidocaine (Group L, n=21), 8.4% sodium bicarbonate (Group B, n=24). After administration of premixed rocuronium 0.6 mg/kg in awake patients, we evaluated intensity of injection pain and withdrawal movement.
Results: We observed that the incidences of pain as well as withdrawal movement was significantly reduced in Group B (20.8%, 0%) compared to Group S (79.3%, 27.6%).
Conclusion: We conclude that sodium bicarbonate addition is effective in relieving the pain and withdrawal movement of rocuronium.
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KEYWORD
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intravenous, lidocaine, normal saline, pain, rocuronium, sodium bicarbonate
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